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HUT / Control Engineering / Research / Microsystems / Solomanda

Solomanda

Manipulation, detection and analysis of biological cells and organelles

A picture of a laboratory rat Laboratory animals and human cell lines have typically been used in drug development, functional genomics, toxicology etc. There are however some problems with such tests:

In order to dispense with these tests, new types of cell cultures are needed that consist of

New methods for handling cells one by one are essential, when this kind of cell cultures will be in use. The Solomanda project aims to develop a system for automatic manipulation, detection and analysis of individual cells. The system consists of

The objectives of HUT and TUT in the project are

  1. to develop manipulation methods of individual biological cells
  2. to develop a micromanipulation system that facilitates high throughput manipulation of individual biological cells

The micromanipulation system consists of a new type of micromanipulator integrated with a pressure microinjector, a control system and a vision system. The vision system and advanced control algorithms will allow high-precision three dimensional positioning of the manipulator. This way cell injections can be automated and the survival rate of injected cells raised from the present values.

In cooperation with